Low Dose Ionising Radiation-Induced Hormesis: Therapeutic Implications to Human Health

The concept of radiation-induced hormesis, whereby a low dose is beneficial and high detrimental, has been gaining attention in the fields molecular biology, environmental toxicology radiation biology. There growing body literature that recognises importance hormetic response not only field, but also with agents. However, there continuing debate on magnitude mechanism response, which could make further contributions, as research tool, to science perhaps eventually public health due potential therapeutic benefits for society. biological phenomena ionising (LDIR) includes bystander effects, adaptive hypersensitivity, radioresistance genomic instability. In this review, detrimental effects LDIR-induced hormesis are explored, together an overview its underlying cellular mechanisms may potentially provide insight implications human future.